957 Sustainable saffron flower extract, the next generation of oral care ingredients for gum health and beauty

نویسندگان

چکیده

Gingivitis is one of the most frequent oral health disorders; P. gingivalis a keystone bacteria in disruption gum barrier and development inflammation. A next generation microbiome friendly, care ingredients dedicated to beauty are gaining interest. In this study, effects Saffron flower extract were investigated on gingipain activity, adhesion growth gingivalis, gingival keratinocytes junction protein (JAM-1) anti-adhesion potential keratinocytes. 3D model epithelium infected with was developed assess damages induced by evaluate saffron 28-day clinical study performed 30 volunteers. The revealed great amounts flavonoids, among them kaempferols quercetins. activity lowered at similar level than competitive inhibitor. demonstrated protective epithelial models. More precisely, alteration cell proteins normal treated supernatant (containing gingipains). application Keratinocytes properties also anti-oxidant properties. Saffran acts specific virulence factor without microbial flora disruption. Inhibition associated decrease protection from impairment. should have preventive plaque accumulation, assumption confirmed clinically. This that promising natural ingredient high against gingivitis periodontitis causing agents.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Issues for the next generation of health care cost analyses.

BACKGROUND Given the characteristics of health care expenditure/cost data-a mass of observations at zero, and skewed positive expenditures, various alternative estimators have been developed that can address the analytical issues these characteristics raise. The field continues to develop new approaches and to evaluate the performance of the existing ones. OBJECTIVES We discuss the strengths ...

متن کامل

Developing the next generation of leaders in oral health.

Given the challenges facing oral health providers as practitioners, community leaders, and educators, expanding dental curricula with an introductory course on leadership is timely and necessary. Such a course will sow the seeds of leadership by defining its importance in the dental profession and creating an understanding that the skills associated with leadership need to be developed over a l...

متن کامل

The oral health benefits of chewing gum.

The use of sugar-free gum provides a proven anti-caries benefit, but other oral health effects are less clearly elucidated. Chewing sugar-free chewing gum promotes a strong flow of stimulated saliva, which helps to provide a number of dental benefits: first, the higher flow rate promotes more rapid oral clearance of sugars; second, the high pH and buffering capacity of the stimulated saliva hel...

متن کامل

Mycosporine-Like Amino Acids: Potential Health and Beauty Ingredients

Human skin is constantly exposed to damaging ultraviolet radiation (UVR), which induces a number of acute and chronic disorders. To reduce the risk of UV-induced skin injury, people apply an additional external protection in the form of cosmetic products containing sunscreens. Nowadays, because of the use of some chemical filters raises a lot of controversies, research focuses on exploring nove...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2023

ISSN: ['1523-1747', '0022-202X']

DOI: https://doi.org/10.1016/j.jid.2023.03.968